Market research report of magnetic bead raw materials in nucleic acid extraction

Market status

The global market size of nucleic acid extraction magnetic beads is expected to reach $2.044 billion in 2024. Although affected by the decline of demand after the epidemic, it still maintains a compound annual growth rate of 5.27% driven by technological iteration. The domestic market shows a rapid growth trend, with a compound growth rate of over 25% from 2020 to 2024, and the scale is expected to exceed 20 billion yuan in 2025. With the advantages of high throughput and automation, the penetration rate of magnetic bead method continues to improve in molecular diagnosis, gene sequencing and other fields.

competition pattern

The market competition pattern is dominated by international giants, with Thermo Fisher, Roche, Qiagen, and Beckman occupying the main share. Its magnetic bead raw materials (such as Thermol’s Dynabeads and Beckman’s AMPure XP) are regarded as the “gold standard” in the industry due to their stability and high compatibility.

Domestic enterprises such as Shanghai LingJun Biotech, Suzhou Beaver Biology and Jifan Biology gradually realize import substitution through technological breakthroughs; Na Micro Technology (listed in 2021) has completed the pilot test of chemiluminescent magnetic beads, and Arun Micro nano (a subsidiary of Zhijiang Biology) has mastered the international leading surface modification technology. In 2024, the market share of domestic magnetic bead manufacturers will increase to 35%, an increase of 15 percentage points compared with 2020. Middle and downstream enterprises such as Huada Intelligent Manufacturing and Mindray Medical will also lay out self-developed magnetic beads. In 2022, CR3 (the market share of the top three enterprises) was not disclosed, but the penetration rate of local enterprises in the middle and low-end market was significantly increased.

Material innovation and function expansion:

Magnetic bead surface modification technology: silicon hydroxyl (SiO₂), carboxyl (-COOH) and other functional groups are optimized to improve nucleic acid adsorption efficiency, such as metal organic polymer modified magnetic beads developed by Wu Lidong team, which has been applied in novel coronavirus detection;

High-throughput automation: the demand for magnetic bead raw materials adapted to the 96-channel extraction instrument has surged, promoting enterprises to develop products with better dispersion and faster magnetic response;

Application scenario extension: In addition to traditional pathogen detection, using magnetic beads in NGS library building, single-cell sequencing, and exosome isolation is expanded, such as AMPure XP magnetic beads in second-generation sequencing for fragment screening.

Application area

Medical diagnosis: infectious diseases (such as COVID-19, HPV), tumor gene testing and genetic disease screening;

Scientific research and pharmaceutical production: gene editing, nucleic acid purification in drug development;

Forensic and agricultural: sample trace DNA extraction and transgene testing.

In the future, as domestic enterprises break through the technical barriers of the whole chain of “magnetic bead-reagent-equipment” and the promotion of precision medical policies, China’s magnetic bead raw material market is expected to achieve a breakthrough in localization in the high-end field, and is expected to form a multi-level competition pattern by 2030. At the supply chain level, the supply of domestic magnetic beads reached 320 million copies in 2024, covering more than 80% of nucleic acid extraction reagent manufacturers.

Supplier

Shanghai Lingjun Biotechnology Co., Ltd. was established in 2016 which is a professional manufacturer of biomagnetic materials and nucleic acid extraction reagents.

We have rich experience in nucleic acid extraction and purification, protein purification, cell separation, chemiluminescence, and other technical fields.

Our products are widely used in many fields, such as medical testing, genetic testing, university research, genetic breeding, and so on. We not only provide products but also can undertake OEM, ODM, and other needs. If you have a related need, please feel free to contact us at sales01@lingjunbio.com.