Professional Manufacturer of Biomagnetic Beads
1. Technological breakthrough and product innovation
A.Nucleic acid extraction technology by magnetic beads has been continuously upgraded
Many enterprises have launched a new generation of magnetic bead method kits, covering whole blood, paraffin-embedded tissue (FFPE), feces, and other types of samples. For example, the magnetic bead method FFPE DNA kit of Beijing Fzhi Medical significantly improves the integrity and purity of DNA by optimizing the cracking and de-linking technology, meets the needs of NGS and liquid biopsy, and helps the accurate diagnosis and treatment of tumors. The magnetic bead soil / fecal DNA kit released by YBio uses a unique grinding bead design to complete extraction and effective removal of humic acid within 1 hour, providing an efficient tool for environmental microbiome research.
B. Acceleration of localization substitution
With independently developed magnetic bead method kits, Chenyu and other enterprises achieve the same performance at one-third of the price of imported products, covering the fields of forensic medicine, agricultural testing, and clinical diagnosis, and promoting the popularization of high-throughput automated nucleic acid extraction equipment. Henan Hui Er Nano and other enterprises to further optimize the surface modification technology of magnetic beads, improve the DNA capture efficiency of trace samples (such as dry blood spots, and forensic examination materials), and support the construction of a large-scale DNA database.
2. Clinical application and scientific research progress
A. Technological breakthrough in early tumor screening and liquid biopsy
The free DNA extraction kit (magnetic bead method) launched by Shanghai Lingjun Biology is applied to tumor liquid biopsy through high-purity cfDNA extraction. Combined with digital PCR technology, it can detect the mutation frequency as low as 0.1%, providing a new scheme for diagnosing lung and colorectal cancer early. The fecal DNA kit simultaneously captures host and microbial DNA, promoting noninvasive screening for colorectal cancer and studying the mechanism of intestinal flora-tumor interaction.
B. Infectious disease and drug resistance surveillance
The CDC used the magnetic bead method whole blood DNA extraction technology for dynamic monitoring of HIV and HBV due to the efficient removal of target proteins and inhibitors. This technology was combined with the CRISPR rapid detection platform to improve the speed of outbreak response.
3. Policy and market dynamics
A. Policies to support precision medical care
The National Health Commission issued the 2025 Biomedical Industry Innovation and Development Plan, which lists the magnetic bead nucleic acid extraction technology as a key supporting technology, encourages the application of domestic kits in medical institutions and third-party testing laboratories, and promotes the registration and review of relevant medical devices.
B. The capital market heat is still unabated
Beijing Fanzhi Medical has completed the C round of financing and raised funds for clinical trials of cancer polygene testing kits and international market expansion. Its FFPE DNA extraction technology has entered the cooperation list of many cancer research centers in Europe and the United States.
4. International cooperation and industry conferences
A. International technical exchanges have been deepened
On February 18, the Global Molecular Diagnosis Summit was held in Shanghai, and the automatic magnetic bead extraction equipment became the focus. Eisheng Biology has reached a strategic cooperation with German Qiagen to jointly develop a nucleic acid purification system suitable for third-generation sequencing, which is expected to be listed in the second half of 2025.
B. The formulation of industry standards was promoted
The Chinese Society of Bioengineering, together with several enterprises, launched the compilation of the Guide for Quality Evaluation of Magnetic Bead Nucleic Acid Extraction Kits, aiming to standardize product performance indicators (such as recovery rate and inhibitor residue limits) and enhance the overall competitiveness of the industry.
Conclusion: The biological industry focuses on technology innovation and clinical application transformation, and the magnetic bead method technology continuously penetrates the diagnosis and scientific research scene with its efficient and safe features. With the help of policy support and capital, domestic substitution and international cooperation are in parallel, accelerating the development of the industry in the direction of precision and automation.
